Fastigium

Fastigium biotechnology consists of the co-transfection of mRNA with helper RNAs.

These single-stranded RNA molecules have several hundred nucleotides and are mixed with the mRNA at a molar ratio of less than 1:100.

The translation efficiency of mRNA is enhanced in transfected cells.

This allows the administration to patients of a lower dose of mRNA to achieve the same level of protein expression.

This will decrease the cost of the mRNA product and improve its tolerance by patients.

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Messenger Biopharma in Lyonbiopole’s newsletter

posted December 22, 2016

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